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30 cardsUSMLE Step 1

USMLE Step 1: High-Yield Associations

Antidotes, translocations, classic findings and key associations for USMLE Step 1.

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Antidote for opioids
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1
Antidote for opioids
Naloxone.
2
Antidote for benzodiazepines
Flumazenil.
3
Antidote for acetaminophen
N-acetylcysteine.
4
Antidote for organophosphates
Atropine and pralidoxime.
5
Antidote for beta blockers
Glucagon.
6
Antidote for heparin
Protamine.
7
Treatment of malignant hyperthermia
Dantrolene.
8
Loop diuretic site of action
Thick ascending limb, Na-K-2Cl cotransporter.
9
Aldosterone action
Increases sodium reabsorption and potassium excretion in the collecting duct.
10
Cardiac output
Heart rate x stroke volume.
11
Mean arterial pressure
Diastolic pressure + one third of pulse pressure.
12
Ejection fraction
Stroke volume / end-diastolic volume.
13
Philadelphia chromosome
t(9;22), BCR-ABL, chronic myeloid leukemia.
14
t(8;14)
c-myc, Burkitt lymphoma.
15
t(14;18)
BCL2, follicular lymphoma.
16
Reed-Sternberg cells
Hodgkin lymphoma.
17
Psammoma bodies and orphan Annie nuclei
Papillary thyroid carcinoma.
18
Kimmelstiel-Wilson nodules
Diabetic nephropathy.
19
Anti-dsDNA
Specific for systemic lupus erythematosus.
20
Anti-CCP
Specific for rheumatoid arthritis.
21
AMA
Antimitochondrial antibodies in primary biliary cholangitis.
22
Currant jelly sputum
Klebsiella pneumoniae.
23
Cold agglutinins
Mycoplasma pneumoniae.
24
Painless chancre
Primary syphilis, Treponema pallidum.
25
Bull's-eye rash
Lyme disease, Borrelia burgdorferi.
26
Type I hypersensitivity
IgE-mediated, immediate.
27
Type IV hypersensitivity
T-cell mediated, delayed.
28
Down syndrome cause
Usually meiotic nondisjunction (trisomy 21).
29
Fragile X
CGG repeat in FMR1.
30
Huntington disease
CAG repeat, autosomal dominant, caudate atrophy.

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