Which combination best describes the components of the Sepsis Six bundle that should be completed within the first hour?

Answer and explanation

Correct answer: B. Blood cultures, lactate, intravenous antibiotics, intravenous fluids, oxygen if needed and urine output measurement

  1. Step 1: The bundle is a set of three diagnostic actions (cultures, lactate, urine output) and three therapeutic actions (antibiotics, fluids, oxygen). Step 2. These are done together and quickly, and antibiotics are not delayed to wait for culture results. Answer: Blood cultures, lactate, intravenous antibiotics, intravenous fluids, oxygen if needed and urine output measurement. Why not the others: Oral antibiotics, steroids, vasopressors as a routine first step, imaging and transfusion are not part of the bundle.

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