Which immediate drug should be offered to a patient with suspected acute coronary syndrome unless contraindicated?

Answer and explanation

Correct answer: D. Aspirin 300 mg orally as a loading dose

  1. Step 1: Platelet aggregation on a ruptured plaque drives acute coronary syndrome. Step 2. Aspirin as a single loading dose of 300 mg is given as soon as possible, followed by further antiplatelet and anticoagulant therapy. Answer: Aspirin 300 mg orally as a loading dose. Why not the others: Diltiazem is not a routine initial drug and may harm if there is left ventricular dysfunction. Warfarin has too slow an onset. Alteplase is not given without a confirmed ST-elevation indication.

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