An oral glucose tolerance test at 26 weeks gives a fasting glucose of 5.2 mmol/L and a 2-hour glucose of 8.1 mmol/L. How does NICE interpret this?

Answer and explanation

Correct answer: A. Gestational diabetes

  1. Step 1: NICE diagnoses gestational diabetes if the fasting value is 5.6 or above, or the 2-hour value is 7.8 or above. Step 2. Either threshold alone is sufficient, and the 2-hour value of 8.1 exceeds 7.8, so the diagnosis is made. Answer: Gestational diabetes. Why not the others: A normal fasting value does not exclude it when the 2-hour value is raised. The result is not described as impaired fasting glycaemia. Overt type 2 diabetes in pregnancy needs higher values.

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