In advanced chronic kidney disease, which biochemical pattern develops in secondary hyperparathyroidism?
Answer and explanation
Correct answer: C. Low calcium, high phosphate and a raised parathyroid hormone level
- Step 1: Failing kidneys retain phosphate and make less active vitamin D. Step 2. Both cause hypocalcaemia, which drives the parathyroid glands to produce more hormone. Answer: Low calcium, high phosphate and a raised parathyroid hormone level. Why not the others: High calcium with raised PTH is primary hyperparathyroidism. High calcium with suppressed PTH suggests malignancy or vitamin D excess. Low calcium with low PTH suggests hypoparathyroidism.
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