Which medication is recommended as a first-line option for neuropathic pain in non-specialist settings according to NICE?
Answer and explanation
Correct answer: D. Amitriptyline, duloxetine, gabapentin or pregabalin
- Step 1: Neuropathic pain responds poorly to standard analgesics. Step 2. NICE lists amitriptyline, duloxetine, gabapentin or pregabalin as initial options, with the choice based on comorbidity and preference. Answer: Amitriptyline, duloxetine, gabapentin or pregabalin. Why not the others: Opioids and paracetamol are not effective for neuropathic pain. Codeine has limited evidence.
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