A 19-year-old man has urethral discharge and a positive nucleic acid amplification test for chlamydia. What is the first-line treatment?

Answer and explanation

Correct answer: C. Doxycycline 100 mg twice daily for 7 days

  1. Step 1: BASHH 2018 guidance prefers doxycycline for uncomplicated chlamydia.
  2. Step 2: Azithromycin is an alternative in pregnancy or poor adherence.
Answer
Doxycycline 100 mg twice daily for 7 days.
Why not the others: Oral flucloxacillin for 7 days: Flucloxacillin has no activity against chlamydia. Ciprofloxacin for 3 days: Ciprofloxacin is not recommended. Single-dose azithromycin as first choice, always: Azithromycin is second-line.

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