Under the Berlin definition, which PaO2/FiO2 ratio on positive end-expiratory pressure of at least 5 cm H2O defines severe Acute Respiratory Distress Syndrome (ARDS)?

Answer and explanation

Correct answer: D. Less than or equal to 100 mmHg

  1. Step 1: The Berlin definition categorizes ARDS severity based on the degree of hypoxemia measured by the PaO2/FiO2 ratio with PEEP or CPAP at least 5 cm H2O.
  2. Step 2: Severe ARDS is defined by a PaO2/FiO2 ratio less than or equal to 100 mmHg.
Answer
Less than or equal to 100 mmHg.
Why not the others: A ratio between 101 and 200 mmHg defines moderate ARDS. A ratio between 201 and 300 mmHg defines mild ARDS. Ratios above 300 mmHg do not meet diagnostic hypoxemia criteria for acute respiratory distress syndrome.

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