Which intravenous solution is contraindicated for fluid resuscitation in a patient with severe traumatic brain injury and intracranial hypertension?
Answer and explanation
Correct answer: B. 0.45 percent sodium chloride
Answer: 0.45 percent sodium chloride.
Why not the others: 0.45 percent saline is hypotonic and drives water intracellularly across the blood-brain barrier, worsening cerebral edema; Plasmalyte-A is an isotonic balanced crystalloid; 0.9 percent saline is isotonic and safe for intracranial resuscitation; 3 percent hypertonic saline actively draws fluid out of brain parenchyma to reduce intracranial pressure.
Why not the others: 0.45 percent saline is hypotonic and drives water intracellularly across the blood-brain barrier, worsening cerebral edema; Plasmalyte-A is an isotonic balanced crystalloid; 0.9 percent saline is isotonic and safe for intracranial resuscitation; 3 percent hypertonic saline actively draws fluid out of brain parenchyma to reduce intracranial pressure.
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