A patient with acute heparin-induced bleeding has an activated partial thromboplastin time of 120 seconds. Which antidote should be administered to neutralize unfractionated heparin?

Answer and explanation

Correct answer: A. Protamine sulfate

Answer: Protamine sulfate.
Why not the others: Vitamin K1 phytomenadione specifically reverses vitamin K antagonists such as warfarin; Aminocaproic acid is an antifibrinolytic agent; Flumazenil is a benzodiazepine receptor antagonist with no effect on coagulation cascades.

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