A patient receiving intravenous vancomycin develops sudden flushing, erythematous rash on the face and neck, and hypotension. What is the immediate nursing action?

Answer and explanation

Correct answer: A. Stop or slow the vancomycin infusion and assess the patient

Answer: Stop or slow the vancomycin infusion and assess the patient.
Why not the others: Rapid infusion of vancomycin causes non-IgE-mediated histamine release (vancomycin infusion reaction). Slowing the infusion resolves symptoms; Potassium replacement is unrelated to histamine release; Increasing the infusion rate worsens histamine release and causes cardiovascular collapse; Switching to penicillin poses severe hypersensitivity risks.

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