Which laboratory parameter must be closely monitored to detect nephrotoxicity in a patient receiving gentamicin aminoglycoside therapy?

Answer and explanation

Correct answer: B. Serum creatinine and trough drug concentrations

Answer: Serum creatinine and trough drug concentrations.
Why not the others: Amylase and lipase monitor pancreatic disorders; Alkaline phosphatase and bilirubin assess hepatic and biliary disorders; Prothrombin time and platelets evaluate coagulation and hemostasis rather than renal proximal tubule injury.

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