A patient taking digoxin develops nausea, blurred yellow vision, and ventricular ectopy. What therapeutic serum digoxin concentration range represents the normal therapeutic window?
Answer and explanation
Correct answer: A. 0.5 to 2.0 ng/mL
Answer: 0.5 to 2.0 ng/mL.
Why not the others: Concentrations above 2.0 ng/mL produce life-threatening cardiac arrhythmias and gastrointestinal toxicity; Concentrations above 4.5 ng/mL represent severe lethal toxicity requiring Fab fragments; 0.05 to 0.2 ng/mL is subtherapeutic.
Why not the others: Concentrations above 2.0 ng/mL produce life-threatening cardiac arrhythmias and gastrointestinal toxicity; Concentrations above 4.5 ng/mL represent severe lethal toxicity requiring Fab fragments; 0.05 to 0.2 ng/mL is subtherapeutic.
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