A patient on chronic corticosteroid therapy undergoes major elective abdominal surgery. Why is stress-dose intravenous hydrocortisone required perioperatively?
Answer and explanation
Correct answer: D. To prevent acute secondary adrenal crisis from hypothalamic-pituitary-adrenal axis suppression
Answer: To prevent acute secondary adrenal crisis from hypothalamic-pituitary-adrenal axis suppression.
Why not the others: Chronic exogenous glucocorticoid use suppresses the adrenal response to surgical stress, risking circulatory collapse; Corticosteroids impair wound healing rather than accelerate it; Corticosteroids do not regulate intraoperative core thermoregulation; Corticosteroids have no direct synergy with cephalosporin bactericidal action.
Why not the others: Chronic exogenous glucocorticoid use suppresses the adrenal response to surgical stress, risking circulatory collapse; Corticosteroids impair wound healing rather than accelerate it; Corticosteroids do not regulate intraoperative core thermoregulation; Corticosteroids have no direct synergy with cephalosporin bactericidal action.
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