What is the causative organism of bacterial vaginosis (BV), characterized by a thin, grayish-white, homogenous vaginal discharge with a characteristic 'fishy' amine odor upon addition of 10% KOH (positive whiff test) and clue cells on wet mount?
Answer and explanation
Correct answer: A. Gardnerella vaginalis along with anaerobic bacteria
- Step 1: Bacterial vaginosis is a dysbiosis characterized by loss of protective hydrogen peroxide-producing lactobacilli and overgrowth of polymicrobial anaerobes, predominantly Gardnerella vaginalis.
- Step 2: Amsel criteria include thin homogenous discharge, pH > 4.5, positive whiff test, and clue cells (> 20% of epithelial cells).
Answer
Gardnerella vaginalis along with anaerobic bacteria.
Why not the others: 'Trichomonas vaginalis' is a flagellated protozoan causing frothy greenish-yellow discharge, strawberry cervix, and motile trichomonads; 'Candida albicans' causes thick curd-like (cottage cheese) discharge with intense pruritus and pseudohyphae; 'Chlamydia trachomatis' causes endocervicitis, not vaginosis.
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