Which neurotransmitter abnormality is most associated with the positive symptoms of schizophrenia?

Answer and explanation

Correct answer: D. Excess dopamine activity in the mesolimbic pathway

  1. Step 1: Hallucinations and delusions are linked to overactive dopamine signaling. Step 2. Antipsychotics block dopamine D2 receptors. Answer: excess mesolimbic dopamine. Why not the others: low serotonin is linked to depression, and low acetylcholine to Alzheimer disease.

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