What type of chemical reaction converts an amide into an amine with one less carbon atom using bromine and sodium hydroxide?
Answer and explanation
Correct answer: D. Hofmann rearrangement
The Hofmann degradation of primary amides (RCONH2 + Br2 + 4 NaOH -> RNH2 + Na2CO3 + 2 NaBr + 2 H2O) yields a primary amine containing one fewer carbon atom via an isocyanate intermediate.
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