What is the most common histological subtype of thyroid carcinoma, typically characterized by psammoma bodies and ground-glass 'Orphan Annie eye' nuclei?
Answer and explanation
Correct answer: C. Papillary thyroid carcinoma
- Step 1: Papillary thyroid carcinoma accounts for over 80-85% of all primary thyroid malignancies.
- Step 2: Characteristic microscopic features include papillary fronds, laminated calcospherites (psammoma bodies), and pale optically clear nuclei ('Orphan Annie eye' nuclei).
- Step 3: It carries an excellent long-term prognosis and spreads primarily via lymphatics.
Answer
Papillary thyroid carcinoma.
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