The scientist's discovery had a profound ______ on modern medicine.

Answer and explanation

Correct answer: B. impact

  1. Step 1: have an impact on 是「對……有影響」的固定搭配。
  2. Step 2: 其餘三個名詞不能與 have a profound ... on 搭配。
Answer
impact.
Why not the others: rumor、absence、accident不符合題意。

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