部屋の中に誰___いません。 (There is no one in the room.)

Answer and explanation

Correct answer: C. も

誰も with a negative verb means no one at all.
Answer: も.
Why not the others: を: を marks an object. で: で marks a place or means. へ: へ marks a direction.

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部屋の中に誰 いません。 (There is… | JLPT Practice (N5 and N4) - Japan