先生___質問しました。 (I asked the teacher a question.)

Answer and explanation

Correct answer: B. に

に marks the person to whom you direct a question.
Answer: に.
Why not the others: を: を marks the thing asked, not the person. が: が would make the teacher the one asking. で: で marks a place or means.

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先生 質問しました。 (I asked the… | JLPT Practice (N5 and N4) - Japan