Which is the most appropriate initial treatment for Addison disease?

Answer and explanation

Correct answer: A. Hydrocortisone with fludrocortisone replacement

  1. Step 1: Addison disease is treated with hydrocortisone with fludrocortisone replacement.
Answer
Hydrocortisone with fludrocortisone replacement.
Why not the others: 'Levothyroxine': it treats thyroid failure. 'High-dose carbimazole': it treats thyrotoxicosis. 'Fludrocortisone alone without glucocorticoid': cortisol replacement is also needed.

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