Which investigation best confirms Systemic lupus erythematosus?

Answer and explanation

Correct answer: C. Anti-double-stranded DNA antibodies

  1. Step 1: The test that best confirms Systemic lupus erythematosus is: anti-double-stranded DNA antibodies.
Answer
Anti-double-stranded DNA antibodies.
Why not the others: 'Anti-cyclic citrullinated peptide antibodies': they are more specific for rheumatoid arthritis. 'Serum uric acid': it is raised in gout. 'Rapid plasma reagin test': it screens for syphilis.

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