A man has ascending symmetrical leg weakness with absent reflexes two weeks after a diarrhoeal illness. What is the most likely diagnosis?

Answer and explanation

Correct answer: D. Guillain-Barre syndrome

  1. Step 1: The picture of ascending weakness with areflexia after an infection fits Guillain-Barre syndrome.
Answer
Guillain-Barre syndrome.
Why not the others: 'Acute transverse myelitis': it gives a sensory level and bladder involvement with brisk reflexes. 'Myasthenia gravis': it causes fatigable weakness without sensory loss or areflexia. 'Spinal cord compression': it gives upper motor neurone signs below a level.

Practise more Clinical cases.

Free questions with an explanation for every one, and full timed Kuwait Medical Licensing Examination (KMLE / KIMS) mock tests.