A 24-year-old has irregular periods, hirsutism, acne and polycystic ovaries on ultrasound. What is the most likely diagnosis?

Answer and explanation

Correct answer: C. Polycystic ovary syndrome

  1. Step 1: The picture of irregular periods with hirsutism fits Polycystic ovary syndrome.
Answer
Polycystic ovary syndrome.
Why not the others: 'Congenital adrenal hyperplasia': it gives early hirsutism with raised 17-hydroxyprogesterone. 'Androgen-secreting ovarian tumour': it gives rapid severe virilisation. 'Hypothyroidism': it gives weight gain and menstrual irregularity without hirsutism.

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