A 52-year-old woman has had no periods for 12 months and has hot flushes and vaginal dryness. What is the most likely diagnosis?

Answer and explanation

Correct answer: D. Menopause

  1. Step 1: The picture of hot flushes after 12 months without periods fits Menopause.
Answer
Menopause.
Why not the others: 'Premature ovarian insufficiency': it occurs before 40 years. 'Hyperthyroidism': it gives heat intolerance and weight loss with a low TSH. 'Pregnancy': it gives amenorrhoea with a positive pregnancy test.

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