Which investigation best confirms Hypothyroidism?

Answer and explanation

Correct answer: D. Serum TSH with free thyroxine

  1. Step 1: The test that best confirms Hypothyroidism is: serum TSH with free thyroxine.
Answer
Serum TSH with free thyroxine.
Why not the others: 'Serum calcium': it is not diagnostic of thyroid failure. 'Thyroid ultrasound alone': it shows structure, not function. 'Fasting glucose': it screens for diabetes.

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