A 12-year-old with sickle cell disease has severe bone pain after dehydration. What is the most likely diagnosis?
Answer and explanation
Correct answer: C. Sickle cell painful crisis
- Step 1: The picture of severe bone pain in sickle cell disease fits Sickle cell painful crisis.
Answer
Sickle cell painful crisis.
Why not the others: 'Osteomyelitis': it gives fever, a localised bone tenderness and raised inflammatory markers. 'Acute chest syndrome': it gives chest pain, cough and new infiltrates. 'Acute abdomen from appendicitis': it gives migrating right iliac fossa pain.
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