A 22-year-old has chronic diarrhoea, weight loss and right iliac fossa pain, with skip lesions and non-caseating granulomas on biopsy. What is the most likely diagnosis?
Answer and explanation
Correct answer: C. Crohn disease
- Step 1: The picture of skip lesions with non-caseating granulomas fits Crohn disease.
Answer
Crohn disease.
Why not the others: 'Ulcerative colitis': it starts in the rectum with continuous mucosal inflammation. 'Intestinal tuberculosis': it is endemic in some regions with caseating granulomas. 'Coeliac disease': it gives villous atrophy responding to gluten withdrawal.
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