A child has diarrhoea, bloating and poor weight gain after cereals are introduced, with positive anti-tissue transglutaminase. What is the most likely diagnosis?

Answer and explanation

Correct answer: D. Coeliac disease

  1. Step 1: The picture of positive anti-tissue transglutaminase antibodies fits Coeliac disease.
Answer
Coeliac disease.
Why not the others: 'Cow milk protein allergy': it presents in infancy after cow milk with eczema or colic. 'Lactose intolerance': it gives bloating and watery stools after milk without villous atrophy. 'Cystic fibrosis': it gives malabsorption with chest infections and raised sweat chloride.

Practise more Paediatric and obstetric cases.

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