A 5-year-old has pallor, bruising, bone pain and hepatosplenomegaly, with blasts on the blood film. What is the most likely diagnosis?
Answer and explanation
Correct answer: D. Acute lymphoblastic leukaemia
- Step 1: The picture of blasts on the blood film with pancytopenia fits Acute lymphoblastic leukaemia.
Answer
Acute lymphoblastic leukaemia.
Why not the others: 'Aplastic anaemia': it gives pancytopenia with a hypocellular marrow and no blasts. 'Idiopathic thrombocytopenic purpura': it gives isolated low platelets after a viral illness. 'Infectious mononucleosis': it gives fever and lymphadenopathy with atypical lymphocytes.
Practise more Paediatric and obstetric cases.
Free questions with an explanation for every one, and full timed Oman Medical Specialty Board Examination (OMSB) mock tests.
More Paediatric and obstetric cases questions
- Which investigation best confirms Acute otitis media?
- Which complication or association is classically linked with Acute otitis media?
- A toddler has a barking cough, a hoarse voice and inspiratory stridor after a cold. What is the most likely diagnosis?
- Which complication or association is classically linked with Croup?
- Which investigation best confirms Bronchiolitis?
- Which complication or association is classically linked with Bronchiolitis?