A 40-year-old man weighs 75 kg and has serum creatinine 0.9 mg/dL. Using Cockcroft-Gault, what is his estimated creatinine clearance (mL/min)?

Answer and explanation

Correct answer: D. 116 mL/min

  1. Step 1: Cockcroft-Gault for men: CrCl = (140 - age) x weight / (72 x creatinine).
  2. Step 2: CrCl = (140 - 40) x 75 / (72 x 0.9) = 116 mL/min.
Answer
116 mL/min.
Why not the others: '98 mL/min' applies the female correction factor of 0.85 to a man; '46 mL/min' uses age instead of 140 minus age; '231 mL/min' doubles the estimate.

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