What is the first-line treatment for anaphylaxis?
Answer and explanation
Correct answer: A. Intramuscular adrenaline into the anterolateral thigh
- Step 1: Adrenaline reverses bronchospasm, vasodilation and mucosal oedema.
- Step 2: The intramuscular route into the thigh gives fast reliable absorption.
Answer
Intramuscular adrenaline into the anterolateral thigh.
Why not the others: 'Intravenous diphenhydramine alone' treats itching but does not reverse airway or circulation collapse; 'Oral prednisolone with observation' acts too slowly in an emergency; 'Subcutaneous salbutamol and antihistamine' is not the first-line drug for anaphylaxis.
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