Which test is best to confirm a diagnosis of Helicobacter pylori infection before eradication therapy?

Answer and explanation

Correct answer: C. Urea breath test

  1. Step 1: Non-invasive tests detect active infection.
  2. Step 2: Serology cannot separate current from past infection, so breath or stool tests are preferred.
Answer
Urea breath test.
Why not the others: 'Serum amylase' is a marker of pancreatitis; 'Random blood glucose' has no link to H. pylori; 'Chest X-ray and bloods' does not detect the bacterium.

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