What is first-line pharmacological treatment for type 2 diabetes in most adults without contraindications?

Answer and explanation

Correct answer: C. Metformin

  1. Step 1: Metformin lowers hepatic glucose output and improves insulin sensitivity.
  2. Step 2: It does not cause weight gain or hypoglycaemia by itself.
Answer
Metformin.
Why not the others: 'Insulin glargine only' is reserved for those not controlled on oral therapy; 'Glibenclamide' carries a higher risk of hypoglycaemia; 'Acarbose' is a less effective option.

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