What is the correct approach to antibiotic prophylaxis for clean elective surgery?
Answer and explanation
Correct answer: A. A single dose within 60 minutes before incision
- Step 1: Tissue levels must be adequate at incision.
- Step 2: Prolonged courses do not reduce infection.
Answer
A single dose within 60 minutes before incision.
Why not the others: 'A course of 7 days after surgery' promotes resistance without benefit; 'Antibiotics only if infection appears' does not prevent infection; 'A dose given after skin closure' is too late to be effective.
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