A child with nephrotic syndrome has heavy proteinuria, hypoalbuminaemia and oedema. What is the most likely histological cause in a 4-year-old?

Answer and explanation

Correct answer: C. Minimal change disease

  1. Step 1: Minimal change disease causes most cases in young children.
  2. Step 2: It responds to corticosteroids.
Answer
Minimal change disease.
Why not the others: 'Membranous nephropathy' is more typical in adults; 'IgA nephropathy' usually presents with haematuria; 'Post-streptococcal glomerulonephritis' is nephritic.

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