Which classes of drugs improve survival in heart failure with reduced ejection fraction?

Answer and explanation

Correct answer: D. ACE inhibitors, evidence-based beta-blockers and mineralocorticoid antagonists

  1. Step 1: ACE inhibitors (or ARBs), carvedilol, bisoprolol or metoprolol succinate, and spironolactone or eplerenone reduce mortality.
Answer
ACE inhibitors, evidence-based beta-blockers and mineralocorticoid antagonists.
Why not the others: Loop diuretics relieve symptoms but do not improve survival.

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