A patient has fatigue, weight gain, cold intolerance and a high TSH with a low free T4. What is the diagnosis?

Answer and explanation

Correct answer: A. Primary hypothyroidism

  1. Step 1: A raised TSH with low free T4 means the thyroid gland itself is failing.
Answer
Primary hypothyroidism.
Why not the others: Secondary hypothyroidism, Subclinical hyperthyroidism and Euthyroid sick syndrome do not fit this picture as well.

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