Answer and explanation

Correct answer: D. A random change in the base sequence of DNA

  1. Step 1: Mutations occur by chance, for example by errors in copying or by radiation. Step 2. They change the base sequence, and the changed gene is a new allele. Answer: a random change in the DNA sequence. Why not the others: Mutations are not planned, transcription makes mRNA, and fertilisation is the joining of gametes.

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