Which test is the best first screening choice for celiac disease in a patient on a normal gluten-containing diet?

Answer and explanation

Correct answer: C. Serum anti-tissue transglutaminase IgA

  1. Step 1: Anti-tTG IgA has high sensitivity and is the preferred first test.
Answer
Serum anti-tissue transglutaminase IgA.
Why not the others: Calprotectin helps in inflammatory bowel disease.

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