A 5-year-old boy has periorbital oedema, albumin of 1.8 g/dL and proteinuria of 4 g per day, without haematuria. What is the most likely histology?

Answer and explanation

Correct answer: B. Minimal change disease

  1. Step 1: Minimal change disease is the commonest cause of nephrotic syndrome in children and responds to corticosteroids. Answer: Minimal change disease. Why not the others: Membranous nephropathy, Focal segmental glomerulosclerosis and IgA nephropathy don't fit.

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