A 48-year-old woman has pruritus and fatigue. Labs show elevated alkaline phosphatase and positive antimitochondrial antibodies. What is the diagnosis?
Answer and explanation
Correct answer: A. Primary biliary cholangitis
- Step 1: AMA positivity points to primary biliary cholangitis. Answer: Primary biliary cholangitis. Why not the others: PSC shows beaded bile ducts and p-ANCA, and autoimmune hepatitis shows ANA with high transaminases.
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