A 55-year-old man with long-standing diabetes has nodular glomerulosclerosis. What is this lesion called?

Answer and explanation

Correct answer: D. Kimmelstiel-Wilson nodules

  1. Step 1: Kimmelstiel-Wilson nodules are typical of diabetic nephropathy. Answer: Kimmelstiel-Wilson nodules. Why not the others: Wire loops occur in lupus nephritis, crescents in rapidly progressive disease and spike-and-dome in membranous nephropathy.

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