A boy has recurrent staphylococcal abscesses and a negative nitroblue tetrazolium test. What is the defect?

Answer and explanation

Correct answer: B. NADPH oxidase

  1. Step 1: Chronic granulomatous disease impairs the respiratory burst. Answer: NADPH oxidase. Why not the others: Myeloperoxidase, Adhesion molecule CD18 and Lysosomal trafficking regulator don't fit.

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