A 40-year-old woman has dry eyes, dry mouth and parotid enlargement. Which antibodies are most likely present?

Answer and explanation

Correct answer: C. Anti-SSA and anti-SSB

  1. Step 1: Sjogren syndrome is associated with anti-SSA and anti-SSB. Answer: Anti-SSA and anti-SSB. Why not the others: Anti-Jo-1 is for polymyositis, anti-topoisomerase for diffuse scleroderma and anti-CCP for rheumatoid arthritis.

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