A patient with opioid use disorder asks for treatment. Which is evidence-based?

Answer and explanation

Correct answer: D. Buprenorphine-naloxone or methadone opioid agonist therapy

  1. Step 1: Agonist therapy lowers overdose death. Step 2. Detox alone has high relapse. Answer: opioid agonist therapy. Why not the others: abrupt withdrawal raises death risk.

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