Why does an enzyme stop working at a very high temperature?

Answer and explanation

Correct answer: D. The protein is denatured and the active site changes shape

  1. Step 1: Heat breaks the weak bonds that hold the protein fold. Step 2. The altered active site no longer fits the substrate. Answer: The protein is denatured. Why not the others: The enzyme is not used up by a reaction, and the cause is its structure.

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