During which phase of the eukaryotic cell cycle does DNA replication occur, doubling the DNA content from to while keeping the chromosome number constant ()?

Answer and explanation

Correct answer: C. S (Synthesis) phase

  1. Step 1: In the eukaryotic cell cycle, interphase consists of , S, and phases.
  2. Step 2: During the S (Synthesis) phase, nuclear DNA replication takes place, doubling the quantity of DNA per cell from to .
  3. Step 3: However, because the newly synthesized sister chromatids remain attached at the centromere, the chromosome number remains unchanged at .
Answer
S (Synthesis) phase.
Why not the others: phase precedes DNA replication and is characterized by cell growth and RNA synthesis; phase is the post-replication stage preparing for mitosis; phase is the quiescent non-proliferative state.

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