The lock-and-key model has been replaced by the induced-fit model. What does the induced-fit model state?
Answer and explanation
Correct answer: C. The active site changes shape slightly as the substrate binds
- Step 1: Binding causes a conformational change that puts strain on substrate bonds and lowers activation energy. Answer: The active site changes shape slightly as the substrate binds. Why not the others: a rigid exact match is the lock-and-key model; the substrate does not change before binding; enzymes are not used up.
Practise more Enzymes.
Free questions with an explanation for every one, and full timed A-Level UK (AQA, Edexcel, OCR) mock tests.
More Enzymes questions
- How does a competitive inhibitor reduce the rate of an enzyme-catalysed reaction?
- The rate of an enzyme reaction is 4 units at 20 °C and 12 units at 30 °C. What is the temperature coefficient (Q10)?
- Why does the rate of an enzyme reaction level off at high substrate concentration?
- Which change is most likely to denature an enzyme in a mammal's cell?